HSF1-dependent and -independent regulation of the mammalian in vivo heat shock response and its impairment in Huntington's disease mouse models

The heat shock response (HSR) is a mechanism to cope with proteotoxic stress by inducing the expression of molecular chaperones and other heat shock response genes. The HSR is evolutionarily well conserved and has been widely studied in bacteria, cell lines and lower eukaryotic model organisms. Howe...

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Detalles Bibliográficos
Autores principales: Neueder, Andreas, Gipson, Theresa A., Batterton, Sophie, Lazell, Hayley J., Farshim, Pamela P., Paganetti, Paolo, Housman, David E., Bates, Gillian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624871/
https://www.ncbi.nlm.nih.gov/pubmed/28970536
http://dx.doi.org/10.1038/s41598-017-12897-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624871/
https://www.ncbi.nlm.nih.gov/pubmed/28970536
http://dx.doi.org/10.1038/s41598-017-12897-0

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