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Multiple regulatory mechanisms of the biological function of NRF3 (NFE2L3) control cancer cell proliferation
Accumulated evidence suggests a physiological relationship between the transcription factor NRF3 (NFE2L3) and cancers. Under physiological conditions, NRF3 is repressed by its endoplasmic reticulum (ER) sequestration. In response to unidentified signals, NRF3 enters the nucleus and modulates gene ex...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624902/ https://www.ncbi.nlm.nih.gov/pubmed/28970512 http://dx.doi.org/10.1038/s41598-017-12675-y |