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Polarized super-resolution structural imaging inside amyloid fibrils using Thioflavine T

Thioflavin T (ThT) is standardly used as a fluorescent marker to detect aggregation of amyloid fibrils by conventional fluorescence microscopy, including polarization resolved imaging that brings information on the orientational order of the fibrils. These techniques are however diffraction limited...

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Detalles Bibliográficos
Autores principales: Shaban, Haitham A., Valades-Cruz, Cesar A., Savatier, Julien, Brasselet, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624930/
https://www.ncbi.nlm.nih.gov/pubmed/28970520
http://dx.doi.org/10.1038/s41598-017-12864-9