Pharmacological use of a novel scaffold, anomeric N,N-diarylamino tetrahydropyran: molecular similarity search, chemocentric target profiling, and experimental evidence

Rational drug design against a determined target (disease, pathway, or protein) is the main strategy in drug discovery. However, regardless of the main strategy, chemists really wonder how to maximize the utility of their new compounds by drug repositioning them as clinical drug candidates in drug d...

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Detalles Bibliográficos
Autores principales: Venkanna, Arramshetti, Kwon, Oh Wook, Afzal, Sualiha, Jang, Cheongyun, Cho, Kyo Hee, Yadav, Dharmendra K., Kim, Kang, Park, Hyeung-geun, Chun, Kwang-Hoon, Kim, Sun Yeou, Kim, Mi-hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624941/
https://www.ncbi.nlm.nih.gov/pubmed/28970544
http://dx.doi.org/10.1038/s41598-017-12082-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624941/
https://www.ncbi.nlm.nih.gov/pubmed/28970544
http://dx.doi.org/10.1038/s41598-017-12082-3

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