Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D(2) receptors

Atypical antipsychotic drugs (APDs) have been hypothesized to show reduced extrapyramidal side effects (EPS) due to their rapid dissociation from the dopamine D(2) receptor. However, support for this hypothesis is limited to a relatively small number of observations made across several decades and u...

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Detalles Bibliográficos
Autores principales: Sykes, David A., Moore, Holly, Stott, Lisa, Holliday, Nicholas, Javitch, Jonathan A., Lane, J. Robert, Charlton, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624946/
https://www.ncbi.nlm.nih.gov/pubmed/28970469
http://dx.doi.org/10.1038/s41467-017-00716-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624946/
https://www.ncbi.nlm.nih.gov/pubmed/28970469
http://dx.doi.org/10.1038/s41467-017-00716-z

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