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Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D(2) receptors
Atypical antipsychotic drugs (APDs) have been hypothesized to show reduced extrapyramidal side effects (EPS) due to their rapid dissociation from the dopamine D(2) receptor. However, support for this hypothesis is limited to a relatively small number of observations made across several decades and u...
Autores principales: | Sykes, David A., Moore, Holly, Stott, Lisa, Holliday, Nicholas, Javitch, Jonathan A., Lane, J. Robert, Charlton, Steven J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624946/ https://www.ncbi.nlm.nih.gov/pubmed/28970469 http://dx.doi.org/10.1038/s41467-017-00716-z |
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