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Role of the Transforming Growth Factor-β in regulating hepatocellular carcinoma oxidative metabolism

Transforming Growth Factor beta (TGF-β) induces tumor cell migration and invasion. However, its role in inducing metabolic reprogramming is poorly understood. Here we analyzed the metabolic profile of hepatocellular carcinoma (HCC) cells that show differences in TGF-β expression. Oxygen consumption...

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Detalles Bibliográficos
Autores principales: Soukupova, Jitka, Malfettone, Andrea, Hyroššová, Petra, Hernández-Alvarez, María-Isabel, Peñuelas-Haro, Irene, Bertran, Esther, Junza, Alexandra, Capellades, Jordi, Giannelli, Gianluigi, Yanes, Oscar, Zorzano, Antonio, Perales, José Carlos, Fabregat, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624948/
https://www.ncbi.nlm.nih.gov/pubmed/28970582
http://dx.doi.org/10.1038/s41598-017-12837-y