Single-cell analysis reveals sexually dimorphic repertoires of Interferon-γ and IL-17A producing T cells in salivary glands of Sjögren’s syndrome mice

The development of Sjögren’s syndrome (SjS) is a dynamic and temporal process with a female predilection. Following the initial influx of immune cells, T cell clusters develop, accelerating the pathology in the salivary glands. Proinflammatory cytokines, IFN-γ and IL-17A, produced by T cells contrib...

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Detalles Bibliográficos
Autores principales: Wanchoo, Arun, Voigt, Alexandria, Sukumaran, Sukesh, Stewart, Carol M., Bhattacharya, Indraneel, Nguyen, Cuong Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624952/
https://www.ncbi.nlm.nih.gov/pubmed/28970488
http://dx.doi.org/10.1038/s41598-017-12627-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624952/
https://www.ncbi.nlm.nih.gov/pubmed/28970488
http://dx.doi.org/10.1038/s41598-017-12627-6

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