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Misoprostol Inhibits Lipopolysaccharide-Induced Pro-inflammatory Cytokine Production by Equine Leukocytes

Pro-inflammatory cytokines including tumor necrosis factor α (TNFα), IL-1β, IL-6, and IL-8 are potent immune mediators that exacerbate multiple equine diseases such as sepsis and laminitis. Unfortunately, safe and effective cytokine-targeting therapies are lacking in horses; therefore, novel mechani...

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Detalles Bibliográficos
Autores principales: Martin, Emily Medlin, Messenger, Kristen M., Sheats, Mary Katherine, Jones, Samuel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624997/
https://www.ncbi.nlm.nih.gov/pubmed/29034249
http://dx.doi.org/10.3389/fvets.2017.00160