Stimulation of Cortico-Subthalamic Projections Amplifies Resting Motor Circuit Activity and Leads to Increased Locomotion in Dopamine-Depleted Mice

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) improves motor function in patients with Parkinson’s disease (PD). STN-DBS enables similar improved motor function, including increased movement speed (reduced bradykinesia), in the 6-OHDA dopamine-depletion mouse model of PD. Previous an...

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Detalles Bibliográficos
Autor principal: Sanders, Teresa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625022/
https://www.ncbi.nlm.nih.gov/pubmed/29033800
http://dx.doi.org/10.3389/fnint.2017.00024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625022/
https://www.ncbi.nlm.nih.gov/pubmed/29033800
http://dx.doi.org/10.3389/fnint.2017.00024

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