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Plasmodium berghei NK65 in Combination with IFN-γ Induces Endothelial Glucocorticoid Resistance via Sustained Activation of p38 and JNK

Malaria-associated acute respiratory distress syndrome (MA-ARDS) is an often lethal complication of malaria. Currently, no adequate therapy for this syndrome exists. Although glucocorticoids (GCs) have been used to improve clinical outcome of ARDS, their therapeutic benefits remain unclear. We previ...

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Detalles Bibliográficos
Autores principales: Zielińska, Karolina A., de Cauwer, Lode, Knoops, Sofie, Van der Molen, Kristof, Sneyers, Alexander, Thommis, Jonathan, De Souza, J. Brian, Opdenakker, Ghislain, De Bosscher, Karolien, Van den Steen, Philippe E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625030/
https://www.ncbi.nlm.nih.gov/pubmed/29033931
http://dx.doi.org/10.3389/fimmu.2017.01199