Cargando…

Plasmodium berghei NK65 in Combination with IFN-γ Induces Endothelial Glucocorticoid Resistance via Sustained Activation of p38 and JNK

Malaria-associated acute respiratory distress syndrome (MA-ARDS) is an often lethal complication of malaria. Currently, no adequate therapy for this syndrome exists. Although glucocorticoids (GCs) have been used to improve clinical outcome of ARDS, their therapeutic benefits remain unclear. We previ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zielińska, Karolina A., de Cauwer, Lode, Knoops, Sofie, Van der Molen, Kristof, Sneyers, Alexander, Thommis, Jonathan, De Souza, J. Brian, Opdenakker, Ghislain, De Bosscher, Karolien, Van den Steen, Philippe E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625030/ https://www.ncbi.nlm.nih.gov/pubmed/29033931 http://dx.doi.org/10.3389/fimmu.2017.01199

Ejemplares similares

Endothelial Response to Glucocorticoids in Inflammatory Diseases
por: Zielińska, Karolina A., et al.
Publicado: (2016)

Glucocorticoid Receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor
por: Petta, Ioanna, et al.
Publicado: (2017)

Adrenal hormones mediate disease tolerance in malaria
por: Vandermosten, Leen, et al.
Publicado: (2018)

Mechanisms Underlying the Functional Cooperation Between PPARα and GRα to Attenuate Inflammatory Responses
por: Bougarne, Nadia, et al.
Publicado: (2019)

The nature of the GRE influences the screening for GR-activity enhancing modulators
por: Dendoncker, Karen, et al.
Publicado: (2017)

The autophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages
por: Mylka, Viacheslav, et al.
Publicado: (2018)

TYK2-induced phosphorylation of Y640 suppresses STAT3 transcriptional activity
por: Mori, Raffaele, et al.
Publicado: (2017)

Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα
por: Ratman, Dariusz, et al.
Publicado: (2016)

Differential induction of malaria liver pathology in mice infected with Plasmodium chabaudi AS or Plasmodium berghei NK65
por: Scaccabarozzi, Diletta, et al.
Publicado: (2018)

Compound A influences gene regulation of the Dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment
por: Desmet, S. J., et al.
Publicado: (2017)

Antiplasmodial Effect of Anthocleista vogelii on Albino Mice Experimentally Infected with Plasmodium berghei berghei (NK 65)
por: Gboeloh, Lebari Barine, et al.
Publicado: (2014)

Coregulator profiling of the glucocorticoid receptor in lymphoid malignancies
por: Clarisse, Dorien, et al.
Publicado: (2017)

11β-hydroxysteroid dehydrogenase type 1 has no effect on survival during experimental malaria but affects parasitemia in a parasite strain-specific manner
por: Vandermosten, L., et al.
Publicado: (2017)

CCR2 Is Dispensable for Disease Resolution but Required for the Restoration of Leukocyte Homeostasis Upon Experimental Malaria-Associated Acute Respiratory Distress Syndrome
por: Pollenus, Emilie, et al.
Publicado: (2021)

Corrigendum: CCR2 Is Dispensable for Disease Resolution but Required for the Restoration of Leukocyte Homeostasis Upon Experimental Malaria-Associated Acute Respiratory Distress Syndrome
por: Pollenus, Emilie, et al.
Publicado: (2022)

Crosstalk between glucocorticoid and mineralocorticoid receptors boosts glucocorticoid-induced killing of multiple myeloma cells
por: Clarisse, Dorien, et al.
Publicado: (2023)

Improved Glucocorticoid Receptor Ligands: Fantastic Beasts, but How to Find Them?
por: Van Moortel, Laura, et al.
Publicado: (2020)

How the glucocorticoid receptor contributes to platinum-based therapy resistance in solid cancer
por: Clarisse, Dorien, et al.
Publicado: (2021)

Neutrophils: Underestimated Players in the Pathogenesis of Multiple Sclerosis (MS)
por: De Bondt, Mirre, et al.
Publicado: (2020)

CCR6 expression reduces mouse survival upon malarial challenge with Plasmodium berghei NK65 strain
por: da Silveira, Eduardo Lani Volpe, et al.
Publicado: (2022)

Pathogenic CD8(+) T Cells Cause Increased Levels of VEGF-A in Experimental Malaria-Associated Acute Respiratory Distress Syndrome, but Therapeutic VEGFR Inhibition Is Not Effective
por: Pham, Thao-Thy, et al.
Publicado: (2017)

In Vivo Antiplasmodial Potential of the Leaf, Mesocarp, and Epicarp of the Raphia hookeri Plant in Mice Infected with Plasmodium berghei NK65
por: Oluyori, Abimbola Peter, et al.
Publicado: (2022)

Matrix Metalloproteinase-9-Generated COOH-, but Not NH(2)-Terminal Fragments of Serum Amyloid A1 Retain Potentiating Activity in Neutrophil Migration to CXCL8, With Loss of Direct Chemotactic and Cytokine-Inducing Capacity
por: Gouwy, Mieke, et al.
Publicado: (2018)

Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study
por: Vandooren, Jennifer, et al.
Publicado: (2017)

Experimental malaria-associated acute respiratory distress syndrome is dependent on the parasite-host combination and coincides with normocyte invasion
por: Vandermosten, Leen, et al.
Publicado: (2018)

The Biologist’s Guide to the Glucocorticoid Receptor’s Structure
por: Deploey, Nick, et al.
Publicado: (2023)

New Perspectives on the Immunopathogenesis and Treatment of Uveitis Associated With Vogt-Koyanagi-Harada Disease
por: Abu El-Asrar, Ahmed M., et al.
Publicado: (2021)

Structure and Expression of Different Serum Amyloid A (SAA) Variants and their Concentration-Dependent Functions During Host  Insults
por: De Buck, Mieke, et al.
Publicado: (2016)

Interferons and other cytokines, genetics and beyond in COVID-19 and autoimmunity
por: Opdenakker, Ghislain, et al.
Publicado: (2021)

Concomitant experimental coinfection by Plasmodium berghei NK65-NY and Ascaris suum downregulates the Ascaris-specific immune response and potentiates Ascaris-associated lung pathology
por: Vieira-Santos, Flaviane, et al.
Publicado: (2021)

Expression of stem cell factor/c-kit signaling pathway components in diabetic fibrovascular epiretinal membranes
por: Abu El-Asrar, Ahmed M., et al.
Publicado: (2010)

Efficacy of Khaya grandifoliola Stem Bark Ethanol Extract in the Treatment of Cerebral Malaria in Swiss albino Mice Using Plasmodium berghei NK65 Strain
por: Guy-Armand, Gamago Nkadeu, et al.
Publicado: (2023)

Effect of combining glucocorticoids with Compound A on glucocorticoid receptor responsiveness in lymphoid malignancies
por: Clarisse, Dorien, et al.
Publicado: (2018)

Long Term Protection after Immunization with P. berghei Sporozoites Correlates with Sustained IFNγ Responses of Hepatic CD8+ Memory T Cells
por: Nganou-Makamdop, Krystelle, et al.
Publicado: (2012)

Improved methods for haemozoin quantification in tissues yield organ-and parasite-specific information in malaria-infected mice
por: Deroost, Katrien, et al.
Publicado: (2012)

Delayed development of the protective IL-17A response following a Giardia muris infection in neonatal mice
por: Paerewijck, Oonagh, et al.
Publicado: (2019)

Modulation of Protein–Protein Interactions for the Development of Novel Therapeutics
por: Petta, Ioanna, et al.
Publicado: (2016)

Immunization of mice with soluble lysate of interferon gamma expressing Plasmodium berghei ANKA induces high IFN-γ production
por: Taylor, Ebenezer, et al.
Publicado: (2017)

Differential Cytokine Profiles upon Comparing Selective versus Classic Glucocorticoid Receptor Modulation in Human Peripheral Blood Mononuclear Cells and Inferior Turbinate Tissue
por: Beck, Ilse M., et al.
Publicado: (2015)

How the Venom from the Ectoparasitoid Wasp Nasonia vitripennis Exhibits Anti-Inflammatory Properties on Mammalian Cell Lines
por: Danneels, Ellen L., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_kff2p9m0jn7vnl1lvqhmoj5a2n