Cargando…

Versatile Roles of the Chromatin Remodeler CHD7 during Brain Development and Disease

CHD7 (Chromo-Helicase-DNA binding protein 7) protein is an ATP-dependent chromatin remodeler. Heterozygous mutation of the CHD7 gene causes a severe congenital disease known as CHARGE syndrome. Most CHARGE syndrome patients have brain structural anomalies, implicating an important role of CHD7 durin...

Descripción completa

Detalles Bibliográficos
Autores principales: Feng, Weijun, Shao, Chunxuan, Liu, Hai-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625114/
https://www.ncbi.nlm.nih.gov/pubmed/29033785
http://dx.doi.org/10.3389/fnmol.2017.00309