Nerve growth factor inhibitor with novel‐binding domain demonstrates nanomolar efficacy in both cell‐based and cell‐free assay systems

Nerve growth factor (NGF), a member of the neurotrophin family, is known to regulate the development and survival of a select population of neurons through the binding and activation of the TrkA receptor. Elevated levels of NGF have been associated with painful pathologies such as diabetic neuropath...

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Detalles Bibliográficos
Autores principales: Kennedy, Allison E., Laamanen, Corey A., Ross, Mitchell S., Vohra, Rahul, Boreham, Douglas R., Scott, John A., Ross, Gregory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625151/
https://www.ncbi.nlm.nih.gov/pubmed/28971611
http://dx.doi.org/10.1002/prp2.339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625151/
https://www.ncbi.nlm.nih.gov/pubmed/28971611
http://dx.doi.org/10.1002/prp2.339

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