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An integrin antagonist (MK‐0429) decreases proteinuria and renal fibrosis in the ZSF1 rat diabetic nephropathy model
Multiple integrins have been implicated in modulating renal function. Modulation of integrin function can lead to pathophysiological processes associated with diabetic nephropathy such as alterations in the glomerular filtration barrier and kidney fibrosis. The complexity of these pathophysiological...
Autores principales: | Zhou, Xiaoyan, Zhang, Ji, Haimbach, Robin, Zhu, Wei, Mayer‐Ezell, Rosemary, Garcia‐Calvo, Margarita, Smith, Elizabeth, Price, Olga, Kan, Yanqing, Zycband, Emanuel, Zhu, Yonghua, Hoek, Maarten, Cox, Jason M., Ma, Lijun, Kelley, David E., Pinto, Shirly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625158/ https://www.ncbi.nlm.nih.gov/pubmed/28971604 http://dx.doi.org/10.1002/prp2.354 |
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