Cargando…

Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors

Diallyl sulfide (DAS), a selective inhibitor of CYP2E1, has shown protective effects against alcohol‐ and acetaminophen‐induced hepatotoxicity in many studies. However, DAS is also a CYP2E1 substrate that on metabolism produces toxic metabolites and causes cytotoxicity. The objective of this study w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rahman, Mohammad A., Midde, Narasimha M., Wu, Xiaoxin, Li, Wei, Kumar, Santosh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625166/ https://www.ncbi.nlm.nih.gov/pubmed/28971616 http://dx.doi.org/10.1002/prp2.362

Ejemplares similares

Effect of Ethanol on the Metabolic Characteristics of HIV-1 Integrase Inhibitor Elvitegravir and Elvitegravir/Cobicistat with CYP3A: An Analysis Using a Newly Developed LC-MS/MS Method
por: Midde, Narasimha M., et al.
Publicado: (2016)

Tobacco and Antiretrovirals Modulate Transporter, Metabolic Enzyme, and Antioxidant Enzyme Expression and Function in Polarized Macrophages
por: Mu, Ying, et al.
Publicado: (2018)

Protective Effects of Diallyl Sulfide and Curcumin Separately against Thallium-Induced Toxicity in Rats
por: Abdel-Daim, Mohamed M., et al.
Publicado: (2015)

Diallyl sulfide protects against dilated cardiomyopathy via inhibition of oxidative stress and apoptosis in mice
por: Pang, Shuo, et al.
Publicado: (2021)

Garlic Extract Diallyl Sulfide (DAS) Activates Nuclear Receptor CAR to Induce the Sult1e1 Gene in Mouse Liver
por: Sueyoshi, Tatsuya, et al.
Publicado: (2011)

Protective Effects of Diallyl Sulfide against Thioacetamide-Induced Toxicity: A Possible Role of Cytochrome P450 2E1
por: Kim, Nam Hee, et al.
Publicado: (2014)

Novel elvitegravir nanoformulation approach to suppress the viral load in HIV-infected macrophages
por: Gong, Yuqing, et al.
Publicado: (2017)

Synergistic Effect of Diallyl Sulfide With Zinc Oxide Nanorods: A Novel and Effective Approach for Treatment of Acute Dermatitis in Model Animals
por: Rauf, Mohd A., et al.
Publicado: (2018)

Diallyl disulfide and diallyl trisulfide in garlic as novel therapeutic agents to overcome drug resistance in breast cancer
por: Malla, RamaRao, et al.
Publicado: (2022)

Developmental differences in the expression of ABC transporters at rat brain barrier interfaces following chronic exposure to diallyl sulfide
por: Koehn, Liam M., et al.
Publicado: (2019)

Diallyl Trisulfide Suppresses Oxidative Stress-Induced Activation of Hepatic Stellate Cells through Production of Hydrogen Sulfide
por: Zhang, Feng, et al.
Publicado: (2017)

Diallyl Sulfide Attenuation of Carcinogenesis in Mammary Epithelial Cells through the Inhibition of ROS Formation, and DNA Strand Breaks
por: Darling-Reed, Selina F., et al.
Publicado: (2021)

Measurement of diallyl disulfide and allyl methyl sulfide emanating from human skin surface and influence of ingestion of grilled garlic
por: Sato, Shodai, et al.
Publicado: (2020)

Exploring the role and mechanisms of diallyl trisulfide and diallyl disulfide in chronic constriction-induced neuropathic pain in rats
por: Wang, Gang, et al.
Publicado: (2020)

Alterations in cellular pharmacokinetics and pharmacodynamics of elvitegravir in response to ethanol exposure in HIV-1 infected monocytic (U1) cells
por: Midde, Narasimha M., et al.
Publicado: (2017)

Reductive Hydroformylation of Isosorbide Diallyl Ether
por: Ternel, Jérémy, et al.
Publicado: (2021)

Differential Cytotoxicity of Acetaminophen in Mouse Macrophage J774.2 and Human Hepatoma HepG2 Cells: Protection by Diallyl Sulfide
por: Raza, Haider, et al.
Publicado: (2015)

Effect of Polyaryl Hydrocarbons on Cytotoxicity in Monocytic Cells: Potential Role of Cytochromes P450 and Oxidative Stress Pathways
por: Ranjit, Sabina, et al.
Publicado: (2016)

Substrate Selectivity of Coumarin Derivatives by Human CYP1 Enzymes: In Vitro Enzyme Kinetics and In Silico Modeling
por: Juvonen, Risto O., et al.
Publicado: (2021)

Monocyte-derived exosomes upon exposure to cigarette smoke condensate alter their characteristics and show protective effect against cytotoxicity and HIV-1 replication
por: Haque, Sanjana, et al.
Publicado: (2017)

Antioxidant and protective effects of extra virgin olive oil incorporated with diallyl sulfide against CCl(4)‐induced acute liver injury in mice
por: Habibi, Emna, et al.
Publicado: (2021)

Bis(diallylbenzimidazolium) tetrabromidocuprate(II)
por: Mys’kiv, Marian, et al.
Publicado: (2008)

THE KINETICS OF PENETRATION : XII. HYDROGEN SULFIDE
por: Jacques, A. G.
Publicado: (1936)

In vitro metabolism, reaction phenotyping, enzyme kinetics, CYP inhibition and induction potential of ataluren
por: Kong, Ronald, et al.
Publicado: (2020)

Kinetic Characteristics of Curcumin and Germacrone in Rat and Human Liver Microsomes: Involvement of CYP Enzymes
por: Su, Shaofeng, et al.
Publicado: (2022)

Plasma exosomes exacerbate alcohol- and acetaminophen-induced toxicity via CYP2E1 pathway
por: Rahman, Mohammad A., et al.
Publicado: (2019)

Diallyl Sulfide-Mediated Modulation of the Fatty Acid Synthase (FASN) Leads to Cancer Cell Death in BaP-Induced Lung Carcinogenesis in Swiss Mice
por: Khan, Arif, et al.
Publicado: (2020)

Diallyl sulfide from garlic suppresses quorum‐sensing systems of Pseudomonas aeruginosa and enhances biosynthesis of three B vitamins through its thioether group
por: Li, Wen‐Ru, et al.
Publicado: (2020)

In Silico Prediction of the Metabolic Resistance of Vitamin D Analogs against CYP3A4 Metabolizing Enzyme
por: Żołek, Teresa, et al.
Publicado: (2022)

Development of 2-arylbenzo[h]quinolone analogs as selective CYP1B1 inhibitors
por: Dong, Jinyun, et al.
Publicado: (2018)

Dietary Bioactive Diallyl Trisulfide in Cancer Prevention and Treatment
por: Puccinelli, Michael T., et al.
Publicado: (2017)

1,4-Phenylene diallyl bis(carbonate)
por: López-Velázquez, Delia, et al.
Publicado: (2023)

Molecular docking of azole drugs and their analogs on CYP121 of Mycobacterium tuberculosis
por: Sundaramurthi, Jagadish Chandrabose, et al.
Publicado: (2011)

Ameliorative Role of Diallyl Disulfide Against Glycerol-induced Nephrotoxicity in Rats
por: Sharma, Ashwani Kumar, et al.
Publicado: (2021)

Combined Kinetic Studies and Computational Analysis on Kojic Acid Analogs as Tyrosinase Inhibitors
por: Lima, Carlyle Ribeiro, et al.
Publicado: (2014)

The roles of CYP2C19 and CYP3A4 in the in vitro metabolism of β‐eudesmol in human liver: Reaction phenotyping and enzyme kinetics
por: Muhamad, Nadda, et al.
Publicado: (2023)

1,3-Diallyl-2-methylbenzimidazolium bromide dihydrate
por: Ennajih, Hamid, et al.
Publicado: (2009)

Diallyl disulfide attenuates acetaminophen-induced renal injury in rats
por: Shin, Jin-Young, et al.
Publicado: (2016)

Fatty liver and alteration of the gut microbiome induced by diallyl disulfide
por: Yang, Yanhong, et al.
Publicado: (2019)

Antimicrobial Effect and the Mechanism of Diallyl Trisulfide against Campylobacter jejuni
por: Tang, Yuanyue, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_a5gl1sa85ao5cdqbl18sjm9dnk