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Eukaryotic Rad50 Functions as A Rod-shaped Dimer

The Rad50 hook interface is crucial for assembly and functions of the Mre11 complex. Previous analyses suggest that Rad50 molecules interact within (intra-complex) or between (inter-complex) dimeric complexes. In this study, we determined the structure of the human Rad50 hook and coiled-coil domain....

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Detalles Bibliográficos
Autores principales: Park, Young Bong, Hohl, Marcel, Padjasek, Michał, Jeong, Eunyoung, Jin, Kyeong Sik, Krężel, Artur, Petrini, John H. J., Cho, Yunje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625350/
https://www.ncbi.nlm.nih.gov/pubmed/28134932
http://dx.doi.org/10.1038/nsmb.3369