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Human Herpesvirus 8 Infects and Replicates in Langerhans Cells and Interstitial Dermal Dendritic Cells and Impairs Their Function

The predominant types of dendritic cells (DC) in the skin and mucosa are Langerhans cells (LC) and interstitial dermal DC (iDDC). LC and iDDC process cutaneous antigens and migrate out of the skin and mucosa to the draining lymph nodes to present antigens to T and B cells. Because of the strategic l...

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Detalles Bibliográficos
Autores principales: Rappocciolo, Giovanna, Jais, Mariel, Piazza, Paolo A., DeLucia, Diana C., Jenkins, Frank J., Rinaldo, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625489/
https://www.ncbi.nlm.nih.gov/pubmed/28768873
http://dx.doi.org/10.1128/JVI.00909-17