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Externally controllable glycan presentation on nanoparticle surfaces to modulate lectin recognition

Nature dynamically controls carbohydrate expression on cells rather than static presentation. Here we report synthetic glycosylated nanoparticles that contain polymeric ‘gates’ to enable external control (via temperature changes) of glycan surface expression, as an alternative to enzymatic control i...

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Detalles Bibliográficos
Autores principales: Won, Sangho, Richards, Sarah-Jane, Walker, Marc, Gibson, Matthew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625543/
https://www.ncbi.nlm.nih.gov/pubmed/28989796
http://dx.doi.org/10.1039/c6nh00202a