Paternal pachytene piRNAs are not required for fertilization, embryonic development and sperm-mediated epigenetic inheritance in mice

Pachytene piRNAs are MIWI-/MILI-bound small RNAs abundantly expressed in pachytene spermatocytes and round spermatids in adult mouse testes. Miwi knockout (KO) male mice are sterile due to spermiogenic arrest. In Caenorhabditis elegans, sperm-borne piRNAs appear to have an epigenetic role during fer...

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Detalles Bibliográficos
Autores principales: Yuan, Shuiqiao, Tang, Chong, Schuster, Andrew, Zhang, Ying, Zheng, Huili, Yan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625633/
https://www.ncbi.nlm.nih.gov/pubmed/28983410
http://dx.doi.org/10.1093/eep/dvw021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625633/
https://www.ncbi.nlm.nih.gov/pubmed/28983410
http://dx.doi.org/10.1093/eep/dvw021

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