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Novel miR-b2122 regulates several ALS-related RNA-binding proteins

Common pathological features of amyotrophic lateral sclerosis (ALS) include cytoplasmic aggregation of several RNA-binding proteins. Out of these RNA-binding proteins, TDP-43, FUS/TLS and RGNEF have been shown to co-aggregate with one another within motor neurons of sporadic ALS (sALS) patients, sug...

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Detalles Bibliográficos
Autores principales: Hawley, Zachary C. E., Campos-Melo, Danae, Strong, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625648/
https://www.ncbi.nlm.nih.gov/pubmed/28969660
http://dx.doi.org/10.1186/s13041-017-0326-7