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Identification of simvastatin-regulated targets associated with JNK activation in DU145 human prostate cancer cell death signaling

The results of this study show that c-Jun N-terminal kinase (JNK) activation was associated with the enhancement of docetaxel-induced cytotoxicity by simvastatin in DU145 human prostate cancer cells. To better understand the basic molecular mechanisms, we investigated simvastatin-regulated targets d...

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Detalles Bibliográficos
Autores principales: Jung, Eun Joo, Chung, Ky Hyun, Kim, Choong Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625694/
https://www.ncbi.nlm.nih.gov/pubmed/28803608
http://dx.doi.org/10.5483/BMBRep.2017.50.9.087