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Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats

BACKGROUND: Estrogen deficiency is thought to be responsible for the higher frequency of aneurysmal subarachnoid hemorrhage in post- than premenopausal women. Estrogen replacement therapy appears to reduce this risk but is associated with significant side effects. We tested our hypothesis that bazed...

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Detalles Bibliográficos
Autores principales: Maekawa, Hidetsugu, Tada, Yoshiteru, Yagi, Kenji, Miyamoto, Takeshi, Kitazato, Keiko T., Korai, Masaaki, Satomi, Junichiro, Hashimoto, Tomoki, Nagahiro, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625708/
https://www.ncbi.nlm.nih.gov/pubmed/28969701
http://dx.doi.org/10.1186/s12974-017-0966-7