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Proteome-wide alterations in an industrial clavulanic acid producing strain of Streptomyces clavuligerus

The usefulness of genetic/metabolic engineering for further improvement of industrial strains is subject of discussion because of the general lack of knowledge on genetic alterations introduced by iterative cycles of random mutagenesis in such strains. An industrial clavulanic acid (CA)-overproducer...

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Detalles Bibliográficos
Autores principales: Ünsaldı, Eser, Kurt-Kızıldoğan, Aslıhan, Voigt, Birgit, Becher, Dörte, Özcengiz, Gülay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625738/
https://www.ncbi.nlm.nih.gov/pubmed/29062960
http://dx.doi.org/10.1016/j.synbio.2016.10.003