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Proteome-wide alterations in an industrial clavulanic acid producing strain of Streptomyces clavuligerus
The usefulness of genetic/metabolic engineering for further improvement of industrial strains is subject of discussion because of the general lack of knowledge on genetic alterations introduced by iterative cycles of random mutagenesis in such strains. An industrial clavulanic acid (CA)-overproducer...
Autores principales: | Ünsaldı, Eser, Kurt-Kızıldoğan, Aslıhan, Voigt, Birgit, Becher, Dörte, Özcengiz, Gülay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625738/ https://www.ncbi.nlm.nih.gov/pubmed/29062960 http://dx.doi.org/10.1016/j.synbio.2016.10.003 |
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