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Icariin Attenuates Synaptic and Cognitive Deficits in an Aβ(1–42)-Induced Rat Model of Alzheimer's Disease

Icariin (ICA), a prenylated flavanol glycoside present in abundant quantities in Epimedium sagittatum, has shown promise in the treatment and prevention of Alzheimer's disease. Damage to synaptic plasticity induced by amyloid-beta-mediated neurotoxicity is considered a main pathological mechani...

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Detalles Bibliográficos
Autores principales: Sheng, Chenxia, Xu, Panpan, Zhou, Kexin, Deng, Dan, Zhang, Chunhu, Wang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625750/
https://www.ncbi.nlm.nih.gov/pubmed/29057264
http://dx.doi.org/10.1155/2017/7464872