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Icariin Attenuates Synaptic and Cognitive Deficits in an Aβ(1–42)-Induced Rat Model of Alzheimer's Disease
Icariin (ICA), a prenylated flavanol glycoside present in abundant quantities in Epimedium sagittatum, has shown promise in the treatment and prevention of Alzheimer's disease. Damage to synaptic plasticity induced by amyloid-beta-mediated neurotoxicity is considered a main pathological mechani...
Autores principales: | Sheng, Chenxia, Xu, Panpan, Zhou, Kexin, Deng, Dan, Zhang, Chunhu, Wang, Zhe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625750/ https://www.ncbi.nlm.nih.gov/pubmed/29057264 http://dx.doi.org/10.1155/2017/7464872 |
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