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Crosstalk between glial and glioblastoma cells triggers the “go-or-grow” phenotype of tumor cells

BACKGROUND: Glioblastoma (GBM), the most malignant primary brain tumor, leads to poor and unpredictable clinical outcomes. Recent studies showed the tumor microenvironment has a critical role in regulating tumor growth by establishing a complex network of interactions with tumor cells. In this conte...

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Detalles Bibliográficos
Autores principales: Oliveira, Ana Isabel, Anjo, Sandra I., Vieira de Castro, Joana, Serra, Sofia C., Salgado, António J., Manadas, Bruno, Costa, Bruno M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625790/
https://www.ncbi.nlm.nih.gov/pubmed/28969644
http://dx.doi.org/10.1186/s12964-017-0194-x