A trade off between catalytic activity and protein stability determines the clinical manifestations of glucose-6-phosphate dehydrogenase (G6PD) deficiency

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common polymorphism and enzymopathy in humans, affecting approximately 400 million people worldwide. It is responsible for various clinical manifestations, including favism, hemolytic anemia, chronic non-spherocytic hemolytic anemia, sp...

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Detalles Bibliográficos
Autores principales: Boonyuen, Usa, Chamchoy, Kamonwan, Swangsri, Thitiluck, Junkree, Thanyaphorn, Day, Nicholas P.J., White, Nicholas J., Imwong, Mallika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625996/
https://www.ncbi.nlm.nih.gov/pubmed/28583873
http://dx.doi.org/10.1016/j.ijbiomac.2017.06.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625996/
https://www.ncbi.nlm.nih.gov/pubmed/28583873
http://dx.doi.org/10.1016/j.ijbiomac.2017.06.002

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