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Derivation of mouse embryonic stem cell lines from tyrosine hydroxylase reporter mice crossed with a human SNCA transgenic mouse model of Parkinson’s disease

Mouse embryonic stem cell (mESC) lines were derived by crossing heterozygous transgenic (tg) mice expressing green fluorescent protein (GFP) under the control of the rat tyrosine hydroxylase (TH) promoter, with homozygous alpha-synuclein (aSYN) mice expressing human mutant SNCA(A53T) under the contr...

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Detalles Bibliográficos
Autores principales: Chumarina, Margarita, Azevedo, Carla, Bigarreau, Julie, Vignon, Clémentine, Kim, Kwang-Soo, Li, Jia-Yi, Roybon, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626016/
https://www.ncbi.nlm.nih.gov/pubmed/28413000
http://dx.doi.org/10.1016/j.scr.2016.12.026