DNMT3A mutations in Chinese childhood acute myeloid leukemia

BACKGROUND: DNA methyltransferase 3A (DNMT3A) mutations have been found in approximately 20% of adult acute myeloid leukemia (AML) patients and in 0% to 1.4% of children with AML, and the hotspots of mutations are mainly located in the catalytic methyltransferase domain, hereinto, mutation R882 acco...

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Detalles Bibliográficos
Autores principales: Li, Weijing, Cui, Lei, Gao, Chao, Liu, Shuguang, Zhao, Xiaoxi, Zhang, Ruidong, Zheng, Huyong, Wu, Minyuan, Li, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
4800
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626129/
https://www.ncbi.nlm.nih.gov/pubmed/28767575
http://dx.doi.org/10.1097/MD.0000000000007620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626129/
https://www.ncbi.nlm.nih.gov/pubmed/28767575
http://dx.doi.org/10.1097/MD.0000000000007620

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