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DNMT3A mutations in Chinese childhood acute myeloid leukemia
BACKGROUND: DNA methyltransferase 3A (DNMT3A) mutations have been found in approximately 20% of adult acute myeloid leukemia (AML) patients and in 0% to 1.4% of children with AML, and the hotspots of mutations are mainly located in the catalytic methyltransferase domain, hereinto, mutation R882 acco...
Autores principales: | Li, Weijing, Cui, Lei, Gao, Chao, Liu, Shuguang, Zhao, Xiaoxi, Zhang, Ruidong, Zheng, Huyong, Wu, Minyuan, Li, Zhigang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626129/ https://www.ncbi.nlm.nih.gov/pubmed/28767575 http://dx.doi.org/10.1097/MD.0000000000007620 |
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