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The effects of stretch activation on ionic selectivity of the TREK-2 K2P K(+) channel

The TREK-2 (KCNK10) K2P potassium channel can be regulated by variety of polymodal stimuli including pressure. In a recent study, we demonstrated that this mechanosensitive K(+) channel responds to changes in membrane tension by undergoing a major structural change from its ‘down’ state to the more...

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Detalles Bibliográficos
Autores principales: Nematian-Ardestani, Ehsan, Jarerattanachat, Viwan, Aryal, Prafulla, Sansom, Mark S. P., Tucker, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626358/
https://www.ncbi.nlm.nih.gov/pubmed/28723241
http://dx.doi.org/10.1080/19336950.2017.1356955