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Quercetin inhibits epithelial–mesenchymal transition, decreases invasiveness and metastasis, and reverses IL-6 induced epithelial–mesenchymal transition, expression of MMP by inhibiting STAT3 signaling in pancreatic cancer cells

Quercetin, a flavone, is multifaceted, having anti-oxidative, anti-inflammatory, and anticancer properties. In the present study, we explored the effects of quercetin on the epithelial–mesenchymal transition (EMT) and invasion of pancreatic cancer cells and the underlying mechanisms. We noted that q...

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Detalles Bibliográficos
Autores principales: Yu, Dinglai, Ye, Tingting, Xiang, Yukai, Shi, Zhehao, Zhang, Jie, Lou, Bin, Zhang, Fan, Chen, Bicheng, Zhou, Mengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626388/
https://www.ncbi.nlm.nih.gov/pubmed/29026320
http://dx.doi.org/10.2147/OTT.S136840