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Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program

Differentiation of lineage-committed cells from multipotent progenitors requires the establishment of accessible chromatin at lineage-specific transcriptional enhancers and promoters, which is mediated by pioneer transcription factors that recruit activating chromatin remodeling complexes. Here we s...

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Detalles Bibliográficos
Autores principales: Loughran, Stephen J., Comoglio, Federico, Hamey, Fiona K., Giustacchini, Alice, Errami, Youssef, Earp, Eleanor, Göttgens, Berthold, Jacobsen, Sten Eirik W., Mead, Adam J., Hendrich, Brian, Green, Anthony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626393/
https://www.ncbi.nlm.nih.gov/pubmed/28899870
http://dx.doi.org/10.1084/jem.20161827