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Dendritic cell and antigen dispersal landscapes regulate T cell immunity

Dendritic cell (DC) subsets with biased capacity for CD4(+) and CD8(+) T cell activation are asymmetrically distributed in lymph nodes (LNs), but how this affects adaptive responses has not been extensively studied. Here we used quantitative imaging to examine the relationships among antigen dispers...

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Detalles Bibliográficos
Autores principales: Gerner, Michael Y., Casey, Kerry A., Kastenmuller, Wolfgang, Germain, Ronald N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626399/
https://www.ncbi.nlm.nih.gov/pubmed/28847868
http://dx.doi.org/10.1084/jem.20170335