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Zika virus has oncolytic activity against glioblastoma stem cells

Glioblastoma is a highly lethal brain cancer that frequently recurs in proximity to the original resection cavity. We explored the use of oncolytic virus therapy against glioblastoma with Zika virus (ZIKV), a flavivirus that induces cell death and differentiation of neural precursor cells in the dev...

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Detalles Bibliográficos
Autores principales: Zhu, Zhe, Gorman, Matthew J., McKenzie, Lisa D., Chai, Jiani N., Hubert, Christopher G., Prager, Briana C., Fernandez, Estefania, Richner, Justin M., Zhang, Rong, Shan, Chao, Tycksen, Eric, Wang, Xiuxing, Shi, Pei-Yong, Diamond, Michael S., Rich, Jeremy N., Chheda, Milan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626408/
https://www.ncbi.nlm.nih.gov/pubmed/28874392
http://dx.doi.org/10.1084/jem.20171093