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Gpr158 mediates osteocalcin’s regulation of cognition
That osteocalcin (OCN) is necessary for hippocampal-dependent memory and to prevent anxiety-like behaviors raises novel questions. One question is to determine whether OCN is also sufficient to improve these behaviors in wild-type mice, when circulating levels of OCN decline as they do with age. Her...
Autores principales: | Khrimian, Lori, Obri, Arnaud, Ramos-Brossier, Mariana, Rousseaud, Audrey, Moriceau, Stéphanie, Nicot, Anne-Sophie, Mera, Paula, Kosmidis, Stylianos, Karnavas, Theodoros, Saudou, Frederic, Gao, Xiao-Bing, Oury, Franck, Kandel, Eric, Karsenty, Gerard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626410/ https://www.ncbi.nlm.nih.gov/pubmed/28851741 http://dx.doi.org/10.1084/jem.20171320 |
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