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Noncovalent interaction-assisted drug delivery system with highly efficient uptake and release of paclitaxel for anticancer therapy

An effective drug delivery system requires efficient drug uptake and release inside cancer cells. Here, we report a novel drug delivery system, in which paclitaxel (PTX) interacts with a novel cell penetrating peptide (CPP) through noncovalent interaction designed based on molecular simulations. Thi...

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Detalles Bibliográficos
Autores principales: Wei, Yuping, Ma, Liang, Zhang, Liang, Xu, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626417/
https://www.ncbi.nlm.nih.gov/pubmed/29026300
http://dx.doi.org/10.2147/IJN.S144322