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Noncovalent interaction-assisted drug delivery system with highly efficient uptake and release of paclitaxel for anticancer therapy
An effective drug delivery system requires efficient drug uptake and release inside cancer cells. Here, we report a novel drug delivery system, in which paclitaxel (PTX) interacts with a novel cell penetrating peptide (CPP) through noncovalent interaction designed based on molecular simulations. Thi...
Autores principales: | Wei, Yuping, Ma, Liang, Zhang, Liang, Xu, Xia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626417/ https://www.ncbi.nlm.nih.gov/pubmed/29026300 http://dx.doi.org/10.2147/IJN.S144322 |
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