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Cholesterol and host cell surface proteins contribute to cell-cell fusion induced by the Burkholderia type VI secretion system 5

Following escape into the cytoplasm of host cells, Burkholderia pseudomallei and the related species Burkholderia thailandensis employ the type VI secretion system 5 (T6SS-5) to induce plasma membrane fusion with an adjacent host cell. This process leads to the formation of multinucleated giant cell...

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Detalles Bibliográficos
Autores principales: Whiteley, Liam, Haug, Maria, Klein, Kristina, Willmann, Matthias, Bohn, Erwin, Chiantia, Salvatore, Schwarz, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626464/
https://www.ncbi.nlm.nih.gov/pubmed/28973030
http://dx.doi.org/10.1371/journal.pone.0185715