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Population FBA predicts metabolic phenotypes in yeast

Using protein counts sampled from single cell proteomics distributions to constrain fluxes through a genome-scale model of metabolism, Population flux balance analysis (Population FBA) successfully described metabolic heterogeneity in a population of independent Escherichia coli cells growing in a d...

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Detalles Bibliográficos
Autores principales: Labhsetwar, Piyush, Melo, Marcelo C. R., Cole, John A., Luthey-Schulten, Zaida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626512/
https://www.ncbi.nlm.nih.gov/pubmed/28886026
http://dx.doi.org/10.1371/journal.pcbi.1005728