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Platelet dysfunction contributes to bleeding complications in patients with probable leptospirosis

BACKGROUND: Severe leptospirosis is frequently complicated by a hemorrhagic diathesis, of which the pathogenesis is still largely unknown. Thrombocytopenia is common, but often not to the degree that spontaneous bleeding is expected. We hypothesized that the hemorrhagic complications are not only re...

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Detalles Bibliográficos
Autores principales: Tunjungputri, Rahajeng N., Gasem, Muhammad Hussein, van der Does, Willemijn, Sasongko, Pandu H., Isbandrio, Bambang, Urbanus, Rolf T., de Groot, Philip G., van der Ven, Andre, de Mast, Quirijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626517/
https://www.ncbi.nlm.nih.gov/pubmed/28934202
http://dx.doi.org/10.1371/journal.pntd.0005915