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Pet10p is a yeast perilipin that stabilizes lipid droplets and promotes their assembly

Pet10p is a yeast lipid droplet protein of unknown function. We show that it binds specifically to and is stabilized by droplets containing triacylglycerol (TG). Droplets isolated from cells with a PET10 deletion strongly aggregate, appear fragile, and fuse in vivo when cells are cultured in oleic a...

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Detalles Bibliográficos
Autores principales: Gao, Qiang, Binns, Derk D., Kinch, Lisa N., Grishin, Nick V., Ortiz, Natalie, Chen, Xiao, Goodman, Joel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626530/
https://www.ncbi.nlm.nih.gov/pubmed/28801319
http://dx.doi.org/10.1083/jcb.201610013