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Vps13-Mcp1 interact at vacuole–mitochondria interfaces and bypass ER–mitochondria contact sites

Membrane contact sites between endoplasmic reticulum (ER) and mitochondria, mediated by the ER–mitochondria encounter structure (ERMES) complex, are critical for mitochondrial homeostasis and cell growth. Defects in ERMES can, however, be bypassed by point mutations in the endosomal protein Vps13 or...

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Detalles Bibliográficos
Autores principales: John Peter, Arun T., Herrmann, Beatrice, Antunes, Diana, Rapaport, Doron, Dimmer, Kai Stefan, Kornmann, Benoît
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626531/
https://www.ncbi.nlm.nih.gov/pubmed/28864540
http://dx.doi.org/10.1083/jcb.201610055