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PICK1 regulates AMPA receptor endocytosis via direct interactions with AP2 α-appendage and dynamin

Clathrin-mediated endocytosis (CME) is used to internalize a diverse range of cargo proteins from the cell surface, often in response to specific signals. In neurons, the rapid endocytosis of GluA2-containing AMPA receptors (AMPARs) in response to NMDA receptor (NMDAR) stimulation causes a reduction...

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Detalles Bibliográficos
Autores principales: Fiuza, Maria, Rostosky, Christine M., Parkinson, Gabrielle T., Bygrave, Alexei M., Halemani, Nagaraj, Baptista, Marcio, Milosevic, Ira, Hanley, Jonathan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626541/
https://www.ncbi.nlm.nih.gov/pubmed/28855251
http://dx.doi.org/10.1083/jcb.201701034