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14-3-3 regulation of Ncd reveals a new mechanism for targeting proteins to the spindle in oocytes

The meiotic spindle is formed without centrosomes in a large volume of oocytes. Local activation of crucial spindle proteins around chromosomes is important for formation and maintenance of a bipolar spindle in oocytes. We found that phosphodocking 14-3-3 proteins stabilize spindle bipolarity in Dro...

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Detalles Bibliográficos
Autores principales: Beaven, Robin, Bastos, Ricardo Nunes, Spanos, Christos, Romé, Pierre, Cullen, C. Fiona, Rappsilber, Juri, Giet, Régis, Goshima, Gohta, Ohkura, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626551/
https://www.ncbi.nlm.nih.gov/pubmed/28860275
http://dx.doi.org/10.1083/jcb.201704120