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Cancer-associated fibroblasts support vascular growth through mechanical force

The role of cancer-associated fibroblasts (CAFs) as regulators of tumor progression, specifically vascular growth, has only recently been described. CAFs are thought to be more mechanically active but how this trait may alter the tumor microenvironment is poorly understood. We hypothesized that enha...

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Detalles Bibliográficos
Autores principales: Sewell-Loftin, Mary Kathryn, Bayer, Samantha Van Hove, Crist, Elizabeth, Hughes, Taylor, Joison, Sofia M., Longmore, Gregory D., George, Steven C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626692/
https://www.ncbi.nlm.nih.gov/pubmed/28974764
http://dx.doi.org/10.1038/s41598-017-13006-x