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Caspase-1 cleaves PPARγ for potentiating the pro-tumor action of TAMs
Tumor-associated macrophages are increasingly viewed as a target of great relevance in the tumor microenvironment, because of their important role in cancer progression and metastasis. However, the endogenous regulatory mechanisms underlying tumor-associated macrophage differentiation remain largely...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626701/ https://www.ncbi.nlm.nih.gov/pubmed/28974683 http://dx.doi.org/10.1038/s41467-017-00523-6 |