Caspase-1 cleaves PPARγ for potentiating the pro-tumor action of TAMs

Tumor-associated macrophages are increasingly viewed as a target of great relevance in the tumor microenvironment, because of their important role in cancer progression and metastasis. However, the endogenous regulatory mechanisms underlying tumor-associated macrophage differentiation remain largely...

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Detalles Bibliográficos
Autores principales: Niu, Zhiyuan, Shi, Qian, Zhang, Wenlong, Shu, Yuxin, Yang, Nanfei, Chen, Bing, Wang, Qingsong, Zhao, Xuyang, Chen, Jiajia, Cheng, Nan, Feng, Xiujing, Hua, Zichun, Ji, Jianguo, Shen, Pingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626701/
https://www.ncbi.nlm.nih.gov/pubmed/28974683
http://dx.doi.org/10.1038/s41467-017-00523-6

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